Whereas within the examination space of St. Bonaventure Hospital, Dr. Shaun Murphy encounters a younger affected person who appears to be like eerily just like his deceased brother, Steve. After discovering his dad and mom have hidden his prognosis from him, Shaun struggles to grasp why he doesn’t deserve to listen to the reality about his personal well being. In the meantime, the workforce can’t work out what retains triggering their sufferers’ more and more extreme allergic reactions and races to search out the trigger earlier than the following one kills one other affected person.